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Zwitterionic betaines over HEPES as the new generation biocompatible pH buffers for cell culture

Good's buffers have been widely applied in cell/organ culture over the past half a century as biocompatible pH stabilizers. However, the emergence of severe adverse effects, such as cellular uptake, lysosomal autophagic activation, and visible light-induced cytotoxicity, raises serious question...

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Detalles Bibliográficos
Autores principales: Liu, Peiming, Sun, Jin, Peng, Wan, Gu, Yahui, Ji, Xiaoxue, Su, Zhi, Liu, Pingsheng, Shen, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817164/
https://www.ncbi.nlm.nih.gov/pubmed/36632510
http://dx.doi.org/10.1016/j.bioactmat.2022.12.028