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Age-related attenuation of cortical synaptic tagging in the ACC is rescued by BDNF or a TrkB receptor agonist in both sex of mice

Long-term potentiation (LTP) is a key cellular mechanism for learning and memory, and recent studies in the hippocampus found that LTP was impaired in aged animals. Previous studies of cortical LTP have focused primarily on the homosynaptic plasticity in adult mice, while fewer studies have looked a...

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Detalles Bibliográficos
Autores principales: Zhou, Si-Bo, Xue, Man, Liu, Weiqi, Chen, Yu-Xin, Chen, Qi-Yu, Lu, Jing-Shan, Wang, Jinjun, Ye, Keqiang, Li, Xu-Hui, Zhuo, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817281/
https://www.ncbi.nlm.nih.gov/pubmed/36604761
http://dx.doi.org/10.1186/s13041-022-00992-x