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Chronic periadolescent leuprolide exposure affects the development of reproductive physiology and behavior of female and male rats differently, but both mature after treatment termination
BACKGROUND: GnRH agonists have been used to halt the development of puberty in children with precocious puberty since the 1980s. Recently, drugs like Lupron Depot(®) (leuprolide acetate), have been used to suppress pubertal progression in adolescents who are questioning their gender identity. Howeve...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817282/ https://www.ncbi.nlm.nih.gov/pubmed/36609535 http://dx.doi.org/10.1186/s13293-022-00485-5 |