Chronic periadolescent leuprolide exposure affects the development of reproductive physiology and behavior of female and male rats differently, but both mature after treatment termination

BACKGROUND: GnRH agonists have been used to halt the development of puberty in children with precocious puberty since the 1980s. Recently, drugs like Lupron Depot(®) (leuprolide acetate), have been used to suppress pubertal progression in adolescents who are questioning their gender identity. Howeve...

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Detalles Bibliográficos
Autores principales: Guarraci, Fay A., Avendano, Layla, Kelly, Megan, Estoesta, Cleriza, Sencherey, Bernard, Valdivia, Hannah S., Gale, Amanda, Yepez, Lily, Belfield, Jasmine B., Carter, Kristen M., Williams, Natalie, Gore, Andrea C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817282/
https://www.ncbi.nlm.nih.gov/pubmed/36609535
http://dx.doi.org/10.1186/s13293-022-00485-5

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