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Mutations of TP53 and genes related to homologous recombination repair in breast cancer with germline BRCA1/2 mutations
BACKGROUND: Germline mutations of breast cancer susceptibility gene BRCA1 and BRCA2 (gBRCA1/2) are associated with elevated risk of breast cancer in young women in Asia. BRCA1 and BRCA2 proteins contribute to genomic stability through homologous recombination (HR)-mediated double-strand DNA break re...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817339/ https://www.ncbi.nlm.nih.gov/pubmed/36604691 http://dx.doi.org/10.1186/s40246-022-00447-3 |