Mutations of TP53 and genes related to homologous recombination repair in breast cancer with germline BRCA1/2 mutations

BACKGROUND: Germline mutations of breast cancer susceptibility gene BRCA1 and BRCA2 (gBRCA1/2) are associated with elevated risk of breast cancer in young women in Asia. BRCA1 and BRCA2 proteins contribute to genomic stability through homologous recombination (HR)-mediated double-strand DNA break re...

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Detalles Bibliográficos
Autores principales: Kim, Jinyong, Jeong, Kyeonghun, Jun, Hyeji, Kim, Kwangsoo, Bae, Jeong Mo, Song, Myung Geun, Yi, Hanbaek, Park, Songyi, Woo, Go-un, Lee, Dae-Won, Kim, Tae-Yong, Lee, Kyung-Hun, Im, Seock-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817339/
https://www.ncbi.nlm.nih.gov/pubmed/36604691
http://dx.doi.org/10.1186/s40246-022-00447-3

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