Targeting fatty acid synthase modulates sensitivity of hepatocellular carcinoma to sorafenib via ferroptosis

BACKGROUND: Sorafenib resistance is a key impediment to successful treatment of patients with advanced hepatocellular carcinoma (HCC) and recent studies have reported reversal of drug resistance by targeting ferroptosis. The present study aimed to explore the association of fatty acid synthase (FASN...

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Detalles Bibliográficos
Autores principales: Li, Yan, Yang, Wenjuan, Zheng, Yuanyuan, Dai, Weiqi, Ji, Jie, Wu, Liwei, Cheng, Ziqi, Zhang, Jie, Li, Jingjing, Xu, Xuanfu, Wu, Jianye, Yang, Mingwei, Feng, Jiao, Guo, Chuanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817350/
https://www.ncbi.nlm.nih.gov/pubmed/36604718
http://dx.doi.org/10.1186/s13046-022-02567-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817350/
https://www.ncbi.nlm.nih.gov/pubmed/36604718
http://dx.doi.org/10.1186/s13046-022-02567-z

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