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Protein kinase B (AKT) upregulation and Thy-1-α(v)β(3) integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis
BACKGROUND: In response to brain injury or inflammation, astrocytes undergo hypertrophy, proliferate, and migrate to the damaged zone. These changes, collectively known as "astrogliosis", initially protect the brain; however, astrogliosis can also cause neuronal dysfunction. Additionally,...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817390/ https://www.ncbi.nlm.nih.gov/pubmed/36609298 http://dx.doi.org/10.1186/s12974-022-02677-7 |