Protein kinase B (AKT) upregulation and Thy-1-α(v)β(3) integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis

BACKGROUND: In response to brain injury or inflammation, astrocytes undergo hypertrophy, proliferate, and migrate to the damaged zone. These changes, collectively known as "astrogliosis", initially protect the brain; however, astrogliosis can also cause neuronal dysfunction. Additionally,...

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Detalles Bibliográficos
Autores principales: Pérez-Núñez, Ramón, Chamorro, Alejandro, González, María Fernanda, Contreras, Pamela, Artigas, Rocío, Corvalán, Alejandro H., van Zundert, Brigitte, Reyes, Christopher, Moya, Pablo R., Avalos, Ana María, Schneider, Pascal, Quest, Andrew F. G., Leyton, Lisette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817390/
https://www.ncbi.nlm.nih.gov/pubmed/36609298
http://dx.doi.org/10.1186/s12974-022-02677-7

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