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A comparison of covariate adjustment approaches under model misspecification in individually randomized trials

Adjustment for baseline covariates in randomized trials has been shown to lead to gains in power and can protect against chance imbalances in covariates. For continuous covariates, there is a risk that the the form of the relationship between the covariate and outcome is misspecified when taking an...

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Detalles Bibliográficos
Autores principales: Tackney, Mia S., Morris, Tim, White, Ian, Leyrat, Clemence, Diaz-Ordaz, Karla, Williamson, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817411/
https://www.ncbi.nlm.nih.gov/pubmed/36609282
http://dx.doi.org/10.1186/s13063-022-06967-6