MicroRNAs miR-584-5p and miR-425-3p Are Up-Regulated in Plasma of Colorectal Cancer (CRC) Patients: Targeting with Inhibitor Peptide Nucleic Acids Is Associated with Induction of Apoptosis in Colon Cancer Cell Lines

SIMPLE SUMMARY: Starting from a list of nine miRNAs found to be dysregulated in the bloodstream of early-stage colon cancer (CRC) patients, the biological effects of the targeting of the most relevant up-regulated miRNAs with anti-miRNA peptide nucleic acids (PNAs) were verified. The down-regulation...

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Detalles Bibliográficos
Autores principales: Gasparello, Jessica, Papi, Chiara, Zurlo, Matteo, Gambari, Laura, Manicardi, Alex, Rozzi, Andrea, Ferrarini, Matteo, Corradini, Roberto, Gambari, Roberto, Finotti, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817681/
https://www.ncbi.nlm.nih.gov/pubmed/36612125
http://dx.doi.org/10.3390/cancers15010128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817681/
https://www.ncbi.nlm.nih.gov/pubmed/36612125
http://dx.doi.org/10.3390/cancers15010128

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