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Comparative Proteomic and Transcriptomic Analysis of the Impact of Androgen Stimulation and Darolutamide Inhibition

SIMPLE SUMMARY: Mass spectrometry-based proteomic analysis of the VCaP prostate cancer cells treated with androgen and the androgen receptor (AR) signaling inhibitor darolutamide revealed a generally good agreement with transcriptomic responses. In some cases, however, the magnitude of changes induc...

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Detalles Bibliográficos
Autores principales: Nevedomskaya, Ekaterina, Sugawara, Tatsuo, Baumgart, Simon J., Lesche, Ralf, Hahne, Hannes, Mumberg, Dominik, Haendler, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817687/
https://www.ncbi.nlm.nih.gov/pubmed/36611998
http://dx.doi.org/10.3390/cancers15010002