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Optical Genome Mapping for Comprehensive Assessment of Chromosomal Aberrations and Discovery of New Fusion Genes in Pediatric B-Acute Lymphoblastic Leukemia

SIMPLE SUMMARY: Acute lymphoblastic leukemia (ALL) is characterized by a large number of chromosomal, structural aberrations associated with risk stratification and treatment outcome. However, conventional karyotyping, FISH and PCR have many limitations in detecting chromosomal aberrations. The aim...

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Detalles Bibliográficos
Autores principales: Gao, Huixia, Xu, Hanli, Wang, Chanjuan, Cui, Lei, Huang, Xiaotong, Li, Weijing, Yue, Zhixia, Tian, Shuo, Zhao, Xiaoxi, Xue, Tianlin, Xing, Tianyu, Li, Jun, Wang, Ying, Zhang, Ruidong, Li, Zhigang, Wang, Tianyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817688/
https://www.ncbi.nlm.nih.gov/pubmed/36612032
http://dx.doi.org/10.3390/cancers15010035