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Optical Genome Mapping for Comprehensive Assessment of Chromosomal Aberrations and Discovery of New Fusion Genes in Pediatric B-Acute Lymphoblastic Leukemia
SIMPLE SUMMARY: Acute lymphoblastic leukemia (ALL) is characterized by a large number of chromosomal, structural aberrations associated with risk stratification and treatment outcome. However, conventional karyotyping, FISH and PCR have many limitations in detecting chromosomal aberrations. The aim...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817688/ https://www.ncbi.nlm.nih.gov/pubmed/36612032 http://dx.doi.org/10.3390/cancers15010035 |