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Optical Genome Mapping for Comprehensive Assessment of Chromosomal Aberrations and Discovery of New Fusion Genes in Pediatric B-Acute Lymphoblastic Leukemia
SIMPLE SUMMARY: Acute lymphoblastic leukemia (ALL) is characterized by a large number of chromosomal, structural aberrations associated with risk stratification and treatment outcome. However, conventional karyotyping, FISH and PCR have many limitations in detecting chromosomal aberrations. The aim...
Autores principales: | Gao, Huixia, Xu, Hanli, Wang, Chanjuan, Cui, Lei, Huang, Xiaotong, Li, Weijing, Yue, Zhixia, Tian, Shuo, Zhao, Xiaoxi, Xue, Tianlin, Xing, Tianyu, Li, Jun, Wang, Ying, Zhang, Ruidong, Li, Zhigang, Wang, Tianyou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817688/ https://www.ncbi.nlm.nih.gov/pubmed/36612032 http://dx.doi.org/10.3390/cancers15010035 |
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