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Epigenetic Insights on PARP-1 Activity in Cancer Therapy

SIMPLE SUMMARY: PARP-1 and poly(ADP-ribosyl)ation control gene expression, DNA repair pathways, and genomic stability in multiple ways, such as affecting chromatin remodelling. This review article summarises how PARP-1 activity directly modifies histone proteins and the enzymes involved in DNA/histo...

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Detalles Bibliográficos
Autores principales:	Pinton, Giulia, Boumya, Sara, Ciriolo, Maria Rosa, Ciccarone, Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817704/ https://www.ncbi.nlm.nih.gov/pubmed/36612003 http://dx.doi.org/10.3390/cancers15010006

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