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p90RSK Regulates p53 Pathway by MDM2 Phosphorylation in Thyroid Tumors
SIMPLE SUMMARY: p90RSK is a downstream effector protein of the MAPK pathway. In many human cancers, the MAPK pathway is constitutively activated due to oncogenic mutations of its components. Consequently, p90RSK is hyperactive and capable of hyper phosphorylating substrates involved in tumorigenesis...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817759/ https://www.ncbi.nlm.nih.gov/pubmed/36612117 http://dx.doi.org/10.3390/cancers15010121 |