GISTs with NTRK Gene Fusions: A Clinicopathological, Immunophenotypic, and Molecular Study

SIMPLE SUMMARY: Wild-type GISTs are generally not sensitive to tyrosine kinase inhibitors. Tropomyosin receptor kinase inhibitors have been approved to be effective in multiple cancers with neurotrophic tyrosine receptor kinase (NTRK) fusions. Although NTRK fusions are rare in wild-type GISTs, the u...

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Detalles Bibliográficos
Autores principales: Cao, Zi, Li, Jiaxin, Sun, Lin, Xu, Zanmei, Ke, Yan, Shao, Bing, Guo, Yuhong, Sun, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817796/
https://www.ncbi.nlm.nih.gov/pubmed/36612101
http://dx.doi.org/10.3390/cancers15010105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817796/
https://www.ncbi.nlm.nih.gov/pubmed/36612101
http://dx.doi.org/10.3390/cancers15010105

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