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5-Azacytidine-Mediated Modulation of the Immune Microenvironment in Murine Acute Myeloid Leukemia
SIMPLE SUMMARY: Leukemic growth results in selective silencing of gene transcripts involved in immune detection, differentiation, and apoptosis. Hypomethylating agents (HMAs), such as 5-azacytidine, have been shown to reprogram the genetic landscape in various cancers to restore both transgene and e...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817798/ https://www.ncbi.nlm.nih.gov/pubmed/36612115 http://dx.doi.org/10.3390/cancers15010118 |