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5-Azacytidine-Mediated Modulation of the Immune Microenvironment in Murine Acute Myeloid Leukemia

SIMPLE SUMMARY: Leukemic growth results in selective silencing of gene transcripts involved in immune detection, differentiation, and apoptosis. Hypomethylating agents (HMAs), such as 5-azacytidine, have been shown to reprogram the genetic landscape in various cancers to restore both transgene and e...

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Detalles Bibliográficos
Autores principales: Ebelt, Nancy D., Manuel, Edwin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817798/
https://www.ncbi.nlm.nih.gov/pubmed/36612115
http://dx.doi.org/10.3390/cancers15010118