EGFR-Tyrosine Kinase Inhibitors Induced Activation of the Autocrine CXCL10/CXCR3 Pathway through Crosstalk between the Tumor and the Microenvironment in EGFR-Mutant Lung Cancer

SIMPLE SUMMARY: Recent studies have sought to evaluate early oncogenic signaling in EGFR-mutant lung cancers under EGFR-TKI treatment, but few studies have evaluated the effect of the tumor microenvironment on persistent tumor cells under EGFR-TKI treatment. Our study demonstrates that CXCL10, a rep...

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Detalles Bibliográficos
Autores principales: Hong, Sook-hee, Kang, Nahyeon, Kim, Okran, Hong, Soon Auck, Park, Juyeon, Kim, Joori, Lee, Myung-Ah, Kang, Jinhyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817815/
https://www.ncbi.nlm.nih.gov/pubmed/36612121
http://dx.doi.org/10.3390/cancers15010124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817815/
https://www.ncbi.nlm.nih.gov/pubmed/36612121
http://dx.doi.org/10.3390/cancers15010124

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