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Role of Patient-Derived Models of Cancer in Translational Oncology

SIMPLE SUMMARY: It was found that long-established tumor-derived cell lines do not adequately reproduce drug sensitivity and behavior of a real human cancers. Therefore, more reliable tumor models that recapitulate the heterogeneity and patho-physiology of patient tumors are under development. The a...

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Detalles Bibliográficos
Autores principales: Idrisova, K. F., Simon, H.-U., Gomzikova, M. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817860/
https://www.ncbi.nlm.nih.gov/pubmed/36612135
http://dx.doi.org/10.3390/cancers15010139