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Single-Cell Transcriptomic Profiles of Lung Pre-Metastatic Niche Reveal Neutrophil and Lymphatic Endothelial Cell Roles in Breast Cancer

SIMPLE SUMMARY: The formation of a pre-metastatic niche (PMN) is important for cancer metastasis. This study revealed a specific lymphatic endothelial cell subpopulation that increased neutrophil recruitment and polarization of N2-type neutrophils in lung PMN. Our study provides an in-depth investig...

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Detalles Bibliográficos
Autores principales: Huang, Yung-Chi, Chang, Chao-Yuan, Wu, Yu-Yuan, Wu, Kuan-Li, Tsai, Ying-Ming, Lee, Hsiao-Chen, Tsai, Eing-Mei, Hsu, Ya-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818165/
https://www.ncbi.nlm.nih.gov/pubmed/36612175
http://dx.doi.org/10.3390/cancers15010176