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Single-Cell Transcriptomic Profiles of Lung Pre-Metastatic Niche Reveal Neutrophil and Lymphatic Endothelial Cell Roles in Breast Cancer
SIMPLE SUMMARY: The formation of a pre-metastatic niche (PMN) is important for cancer metastasis. This study revealed a specific lymphatic endothelial cell subpopulation that increased neutrophil recruitment and polarization of N2-type neutrophils in lung PMN. Our study provides an in-depth investig...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818165/ https://www.ncbi.nlm.nih.gov/pubmed/36612175 http://dx.doi.org/10.3390/cancers15010176 |