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Withaferin A Enhances Mitochondrial Biogenesis and BNIP3-Mediated Mitophagy to Promote Rapid Adaptation to Extreme Hypoxia

Rapid adaptation to extreme hypoxia is a challenging problem, and there is no effective scheme to achieve rapid adaptation to extreme hypoxia. In this study, we found that withaferin A (WA) can significantly reduce myocardial damage, maintain cardiac function, and improve survival in rats in extreme...

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Detalles Bibliográficos
Autores principales: Zhao, Ruzhou, Xu, Yixin, Wang, Xiaobo, Zhou, Xiang, Liu, Yanqi, Jiang, Shuai, Zhang, Lin, Yu, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818179/
https://www.ncbi.nlm.nih.gov/pubmed/36611879
http://dx.doi.org/10.3390/cells12010085