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Notch1 Protects against Ischemic-Reperfusion Injury by Suppressing PTEN-Pink1-Mediated Mitochondrial Dysfunction and Mitophagy

Background: Myocardial ischemia/reperfusion injury is associated with adverse cardiovascular outcomes after acute myocardial infarction. However, the molecular mechanism of ischemia/reperfusion injury remains unclear. Mitochondria dysfunction is a participant in and regulator of myocardial ischemia-...

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Detalles Bibliográficos
Autores principales: Xu, Qirong, Liu, Sheng, Gong, Qiang, Zhu, Rongrong, Liu, Jichun, Wu, Qicai, Zhou, Xueliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818205/
https://www.ncbi.nlm.nih.gov/pubmed/36611931
http://dx.doi.org/10.3390/cells12010137