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Sigma-1 Receptor as a Protective Factor for Diabetes-Associated Cognitive Dysfunction via Regulating Astrocytic Endoplasmic Reticulum-Mitochondrion Contact and Endoplasmic Reticulum Stress

The prevalence of diabetes-associated cognitive dysfunction (DACD) has increased to 13.5%. Dementia, as the most severe DACD, is the second leading cause of death in patients with diabetes mellitus. Hence, the potential mechanisms of DACD for slowing or halting its progression need to be urgently ex...

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Detalles Bibliográficos
Autores principales: Du, Mengyu, Jiang, Tao, He, Shuxuan, Cheng, Bo, Zhang, Xin, Li, Liya, Yang, Lan, Gao, Wei, Li, Yansong, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818229/
https://www.ncbi.nlm.nih.gov/pubmed/36611988
http://dx.doi.org/10.3390/cells12010197