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PGC-1α Regulates Cell Proliferation, Migration, and Invasion by Modulating Leucyl-tRNA Synthetase 1 Expression in Human Colorectal Cancer Cells

SIMPLE SUMMARY: There are still controversies about the roles of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) and leucyl-tRNA synthetase 1 (LARS1) in cancer. In this study, we examined whether the effects of PGC-1α on cell proliferation and invasion were mediated by modulatio...

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Detalles Bibliográficos
Autores principales: Cho, Jun Gi, Park, Su-Jeong, Han, Sang-Heum, Park, Joo-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818264/
https://www.ncbi.nlm.nih.gov/pubmed/36612155
http://dx.doi.org/10.3390/cancers15010159