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Intrinsic and Extrinsic Transcriptional Profiles That Affect the Clinical Response to PD-1 Inhibitors in Patients with Non–Small Cell Lung Cancer

SIMPLE SUMMARY: Monoclonal antibodies targeting the programmed death 1 (PD-1) receptor and its ligand (PD-L1) have demonstrated improved clinical response and survival in non-small cell lung cancer (NSCLC). Although extrinsic immunologic factors play important roles in the regulation of PD-L1 and PD...

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Detalles Bibliográficos
Autores principales: Byeon, Hye Eun, Haam, Seokjin, Han, Jae Ho, Lee, Hyun Woo, Koh, Young Wha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818269/
https://www.ncbi.nlm.nih.gov/pubmed/36612193
http://dx.doi.org/10.3390/cancers15010197