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Transcriptomic Analysis Reveals JAK2/MPL-Independent Effects of Calreticulin Mutations in a C. elegans Model

There is growing evidence that Ph-negative myeloproliferative neoplasms (MPNs) are disorders in which multiple molecular mechanisms are significantly disturbed. Since their discovery, CALR driver mutations have been demonstrated to trigger pathogenic mechanisms apart from the well-documented activat...

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Detalles Bibliográficos
Autores principales: Guijarro-Hernández, Ana, Eder-Azanza, Laura, Hurtado, Cristina, Navarro-Herrera, David, Ezcurra, Begoña, Novo, Francisco Javier, Cabello, Juan, Vizmanos, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818371/
https://www.ncbi.nlm.nih.gov/pubmed/36611979
http://dx.doi.org/10.3390/cells12010186