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Single-Cell and CellChat Resolution Identifies Collecting Duct Cell Subsets and Their Communications with Adjacent Cells in PKD Kidneys

ADPKD is a genetic disorder with a molecular complexity that remains poorly understood. In this study, we sampled renal cells to construct a comprehensive and spatiotemporally resolved gene expression atlas in whole Pkd1 mutant polycystic mouse kidneys at single-cell resolution. We characterized cel...

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Detalles Bibliográficos
Autores principales: Li, Linda Xiaoyan, Zhang, Xu, Zhang, Hongbing, Agborbesong, Ewud, Zhou, Julie Xia, Calvet, James P., Li, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818381/
https://www.ncbi.nlm.nih.gov/pubmed/36611841
http://dx.doi.org/10.3390/cells12010045