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Megalin Orchestrates FcRn Endocytosis and Trafficking

The neonatal Fc receptor (FcRn) is highly expressed in the renal proximal tubule and is important for the reclamation of albumin by cellular transcytosis to prevent its loss in the urine. The initial event of this transcellular transport mechanism is the endocytosis of albumin by the apical scavenge...

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Detalles Bibliográficos
Autores principales: Dahlke, Eileen, Anan, Yaman, Klie, Lea Maximiliane, Hartkopf, Ariane Elisabeth, Theilig, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818419/
https://www.ncbi.nlm.nih.gov/pubmed/36611847
http://dx.doi.org/10.3390/cells12010053