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Megalin Orchestrates FcRn Endocytosis and Trafficking
The neonatal Fc receptor (FcRn) is highly expressed in the renal proximal tubule and is important for the reclamation of albumin by cellular transcytosis to prevent its loss in the urine. The initial event of this transcellular transport mechanism is the endocytosis of albumin by the apical scavenge...
Autores principales: | Dahlke, Eileen, Anan, Yaman, Klie, Lea Maximiliane, Hartkopf, Ariane Elisabeth, Theilig, Franziska |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818419/ https://www.ncbi.nlm.nih.gov/pubmed/36611847 http://dx.doi.org/10.3390/cells12010053 |
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