PNPLA3(I148M) Inhibits Lipolysis by Perilipin-5-Dependent Competition with ATGL

The single nucleotide polymorphism I148M of the lipase patatin-like phospholipase domain containing 3 (PNPLA3) is associated with an unfavorable prognosis in alcoholic and non-alcoholic steatohepatitis (ASH, NASH), with progression to liver cirrhosis and development of hepatocellular carcinoma. In t...

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Detalles Bibliográficos
Autores principales: Witzel, Hagen Roland, Schwittai, Inga Maria Gertrud, Hartmann, Nils, Mueller, Sebastian, Schattenberg, Jörn M., Gong, Xue-Min, Backs, Johannes, Schirmacher, Peter, Schuppan, Detlef, Roth, Wilfried, Straub, Beate Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818421/
https://www.ncbi.nlm.nih.gov/pubmed/36611868
http://dx.doi.org/10.3390/cells12010073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818421/
https://www.ncbi.nlm.nih.gov/pubmed/36611868
http://dx.doi.org/10.3390/cells12010073

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