Integrative Multi-OMICs Identifies Therapeutic Response Biomarkers and Confirms Fidelity of Clinically Annotated, Serially Passaged Patient-Derived Xenografts Established from Primary and Metastatic Pediatric and AYA Solid Tumors

SIMPLE SUMMARY: Solid tumors account for ~60% of pediatric, as well as adolescent and young adult (AYA), cancers, and outcomes for patients with these progressive diseases remain poor. This highlights the critical need to develop tumor models from patients with aggressive cancers so that oncogenic s...

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Detalles Bibliográficos
Autores principales: Pandya, Pankita H., Jannu, Asha Jacob, Bijangi-Vishehsaraei, Khadijeh, Dobrota, Erika, Bailey, Barbara J., Barghi, Farinaz, Shannon, Harlan E., Riyahi, Niknam, Damayanti, Nur P., Young, Courtney, Malko, Rada, Justice, Ryli, Albright, Eric, Sandusky, George E., Wurtz, L. Daniel, Collier, Christopher D., Marshall, Mark S., Gallagher, Rosa I., Wulfkuhle, Julia D., Petricoin, Emanuel F., Coy, Kathy, Trowbridge, Melissa, Sinn, Anthony L., Renbarger, Jamie L., Ferguson, Michael J., Huang, Kun, Zhang, Jie, Saadatzadeh, M. Reza, Pollok, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818438/
https://www.ncbi.nlm.nih.gov/pubmed/36612255
http://dx.doi.org/10.3390/cancers15010259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818438/
https://www.ncbi.nlm.nih.gov/pubmed/36612255
http://dx.doi.org/10.3390/cancers15010259

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