The Consequences of GBA Deficiency in the Autophagy–Lysosome System in Parkinson’s Disease Associated with GBA

GBA gene variants were the first genetic risk factor for Parkinson’s disease. GBA encodes the lysosomal enzyme glucocerebrosidase (GBA), which is involved in sphingolipid metabolism. GBA exhibits a complex physiological function that includes not only the degradation of its substrate glucosylceramid...

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Detalles Bibliográficos
Autores principales: Pradas, Eddie, Martinez-Vicente, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818455/
https://www.ncbi.nlm.nih.gov/pubmed/36611984
http://dx.doi.org/10.3390/cells12010191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818455/
https://www.ncbi.nlm.nih.gov/pubmed/36611984
http://dx.doi.org/10.3390/cells12010191

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