ML216 Prevents DNA Damage-Induced Senescence by Modulating DBC1–BLM Interaction

DNA damage is the major cause of senescence and apoptosis; however, the manner by which DNA-damaged cells become senescent remains unclear. We demonstrate that DNA damage leads to a greater level of senescence rather than apoptosis in DBC1-deficient cells. In addition, we show that BLM becomes degra...

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Detalles Bibliográficos
Autores principales: Cui, Feng, Han, Xueying, Zhang, Xiaoqian, Wang, Siqi, Liang, Na, Tan, Qing, Sha, Wuga, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818470/
https://www.ncbi.nlm.nih.gov/pubmed/36611939
http://dx.doi.org/10.3390/cells12010145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818470/
https://www.ncbi.nlm.nih.gov/pubmed/36611939
http://dx.doi.org/10.3390/cells12010145

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