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Lower Metabolic Potential and Impaired Metabolic Flexibility in Human Lymph Node Stromal Cells from Patients with Rheumatoid Arthritis

Cellular metabolism is important for determining cell function and shaping immune responses. Studies have shown a crucial role for stromal cells in steering proper immune responses in the lymph node microenvironment. These lymph node stromal cells (LNSCs) tightly regulate immune tolerance. We hypoth...

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Detalles Bibliográficos
Autores principales: de Jong, Tineke A., Semmelink, Johanna F., Denis, Simone W., Bolt, Janne W., Maas, Mario, van de Sande, Marleen G. H., Houtkooper, Riekelt H. L., van Baarsen, Lisa G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818527/
https://www.ncbi.nlm.nih.gov/pubmed/36611795
http://dx.doi.org/10.3390/cells12010001