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A Multidisciplinary Approach Establishes a Link between Transglutaminase 2 and the Kv10.1 Voltage-Dependent K(+) Channel in Breast Cancer

SIMPLE SUMMARY: This work intends to unravel one of the roles played by transglutaminase 2 within the cell. We highlighted its physical interaction with the voltage-dependent Kv10.1 K(+) channel, an important target of therapies in breast cancer. The use of transglutaminase 2 inhibitors can selectiv...

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Detalles Bibliográficos
Autores principales: Canella, Rita, Brugnoli, Federica, Gallo, Mariana, Keillor, Jeffrey W., Terrazzan, Anna, Ferrari, Elena, Grassilli, Silvia, Gates, Eric W. J., Volinia, Stefano, Bertagnolo, Valeria, Bianchi, Nicoletta, Bergamini, Carlo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818547/
https://www.ncbi.nlm.nih.gov/pubmed/36612174
http://dx.doi.org/10.3390/cancers15010178