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12-O-tetradecanoylphorbol-13-acetate Reduces Activation of Hepatic Stellate Cells by Inhibiting the Hippo Pathway Transcriptional Coactivator YAP

Although protein kinase C (PKC) regulates various biological activities, including cell proliferation, differentiation, migration, tissue remodeling, gene expression, and cell death, the antifibrotic effect of PKC in myofibroblasts is not fully understood. We investigated whether 12-O-tetradecanoylp...

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Detalles Bibliográficos
Autores principales: Kim, Chang Wan, Yoon, Yongdae, Kim, Moon Young, Baik, Soon Koo, Ryu, Hoon, Park, Il Hwan, Eom, Young Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818550/
https://www.ncbi.nlm.nih.gov/pubmed/36611885
http://dx.doi.org/10.3390/cells12010091