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Azilsartan Modulates HMGB1/NF-κB/p38/ERK1/2/JNK and Apoptosis Pathways during Renal Ischemia Reperfusion Injury

Renal ischemia/reperfusion (IR) injury is characterized by an unexpected impairment of blood flow to the kidney. Azilsartan is an angiotensin receptor blocker that is approved for the management of hypertension. The present study aimed to investigate, on molecular basics, the nephroprotective activi...

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Detalles Bibliográficos
Autores principales: Alaaeldin, Rania, Bakkar, Sally M., Mohyeldin, Reham H., Ali, Fares E. M., Abdel-Maqsoud, Nehad M. Reda, Fathy, Moustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818604/
https://www.ncbi.nlm.nih.gov/pubmed/36611978
http://dx.doi.org/10.3390/cells12010185