Novel Specific Pyruvate Kinase M2 Inhibitor, Compound 3h, Induces Apoptosis and Autophagy through Suppressing Akt/mTOR Signaling Pathway in LNCaP Cells

SIMPLE SUMMARY: Prostate cancer is a serious threat to male health worldwide; however, chemotherapy remains an urgent problem because of resistance and insensitivity to androgen-deprivation therapy. Therefore, discovering novel molecules and chemotherapy can provide a new strategy. Pyruvate kinase M...

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Detalles Bibliográficos
Autores principales: Jiang, Chunxue, Zhao, Xiaodi, Jeong, Taejoo, Kang, Ju Young, Park, Jae Hyeon, Kim, In Su, Kim, Hyung Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818605/
https://www.ncbi.nlm.nih.gov/pubmed/36612260
http://dx.doi.org/10.3390/cancers15010265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818605/
https://www.ncbi.nlm.nih.gov/pubmed/36612260
http://dx.doi.org/10.3390/cancers15010265

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