Cargando…

CK2-Mediated Phosphorylation Upregulates the Stability of USP13 and Promotes Ovarian Cancer Cell Proliferation

SIMPLE SUMMARY: Ubiquitin-specific Peptidase 13 (USP13) is highly amplified and promotes tumorigenesis and metastasis in ovarian cancer. However, post-translational modifications and their functions on USP13 are largely unknown. This study revealed that USP13 is phosphorylated at Thr122, which upreg...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Juntae, Zhang, Jinmin, Mok, Boram, Han, Cecil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818633/
https://www.ncbi.nlm.nih.gov/pubmed/36612196
http://dx.doi.org/10.3390/cancers15010200