Multiformin-Type Azaphilones Prevent SARS-CoV-2 Binding to ACE2 Receptor

Protein microarray screenings identified fungal natural products from the azaphilone family as potent inhibitors of SARS-CoV-2 spike protein binding to host ACE2 receptors. Cohaerin F, as the most potent substance from the cohaerin group, led to more than 50% less binding of ACE2 and SARS-CoV-2 spik...

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Detalles Bibliográficos
Autores principales: Jansen-Olliges, Linda, Chatterjee, Shambhabi, Jia, Lili, Stahl, Frank, Bär, Christian, Stadler, Marc, Surup, Frank, Zeilinger, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818685/
https://www.ncbi.nlm.nih.gov/pubmed/36611877
http://dx.doi.org/10.3390/cells12010083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818685/
https://www.ncbi.nlm.nih.gov/pubmed/36611877
http://dx.doi.org/10.3390/cells12010083

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