The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1

Therapy resistance is still a major reason for treatment failure in colorectal cancer (CRC). Previously, we identified the E3 ubiquitin ligase TRIM25 as a novel suppressor of caspase-2 translation which contributes to the apoptosis resistance of CRC cells towards chemotherapeutic drugs. Here, we rep...

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Detalles Bibliográficos
Autores principales: Nasrullah, Usman, Stanke, Kristina, Recknagel, Victoria, Bozkurt, Süleyman, Wurzel, Patrick, Gauer, Stefan, Imre, Gergely, Münch, Christian, Pfeilschifter, Josef, Eberhardt, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818768/
https://www.ncbi.nlm.nih.gov/pubmed/36611995
http://dx.doi.org/10.3390/cells12010201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818768/
https://www.ncbi.nlm.nih.gov/pubmed/36611995
http://dx.doi.org/10.3390/cells12010201

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