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RNF213 Loss-of-Function Promotes Angiogenesis of Cerebral Microvascular Endothelial Cells in a Cellular State Dependent Manner

Enhanced and aberrant angiogenesis is one of the main features of Moyamoya disease (MMD) pathogenesis. The ring finger protein 213 (RNF213) and the variant p.R4810K have been linked with higher risks of MMD and intracranial arterial occlusion development in east Asian populations. The role of RNF213...

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Detalles Bibliográficos
Autores principales: Roy, Vincent, Brodeur, Alyssa, Touzel Deschênes, Lydia, Dupré, Nicolas, Gros-Louis, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818782/
https://www.ncbi.nlm.nih.gov/pubmed/36611871
http://dx.doi.org/10.3390/cells12010078