Oral Squamous Cell Carcinoma Cells with Acquired Resistance to Erlotinib Are Sensitive to Anti-Cancer Effect of Quercetin via Pyruvate Kinase M2 (PKM2)

Oral squamous cell carcinoma (OSCC) frequently carries high epidermal growth factor receptor (EGFR) expression. Erlotinib, a small molecule tyrosine kinase inhibitor (TKI), is an effective inhibitor of EGFR activity; however, resistance to this drug can occur, limiting therapeutic outcomes. Therefor...

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Detalles Bibliográficos
Autores principales: Chan, Chien-Yi, Hong, Shih-Cing, Chang, Chin-Ming, Chen, Yuan-Hong, Liao, Pin-Chen, Huang, Chun-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818869/
https://www.ncbi.nlm.nih.gov/pubmed/36611972
http://dx.doi.org/10.3390/cells12010179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818869/
https://www.ncbi.nlm.nih.gov/pubmed/36611972
http://dx.doi.org/10.3390/cells12010179

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