Lessons from Using Genetically Engineered Mouse Models of MYC-Induced Lymphoma

Oncogenic overexpression of MYC leads to the fatal deregulation of signaling pathways, cellular metabolism, and cell growth. MYC rearrangements are found frequently among non-Hodgkin B-cell lymphomas enforcing MYC overexpression. Genetically engineered mouse models (GEMMs) were developed to understa...

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Detalles Bibliográficos
Autores principales: Winkler, René, Piskor, Eva-Maria, Kosan, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818924/
https://www.ncbi.nlm.nih.gov/pubmed/36611833
http://dx.doi.org/10.3390/cells12010037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818924/
https://www.ncbi.nlm.nih.gov/pubmed/36611833
http://dx.doi.org/10.3390/cells12010037

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