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The CAPRA&PDE4D5/7/9 Prognostic Model Is Significantly Associated with Adverse Post-Surgical Pathology Outcomes

SIMPLE SUMMARY: PDE4D5, PDE4D7 and PDE4D9 are prostate expressed transcripts of the PDE4D gene coding for cAMP degrading phosphodiesterases. These genes have been implicated in the change of prostate cancer from an androgen sensitive to an androgen insensitive, treatment resistant state. CAPRA is a...

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Detalles Bibliográficos
Autores principales: Gulliver, Chloe, Huss, Sebastian, Semjonow, Axel, Baillie, George S., Hoffmann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9818961/
https://www.ncbi.nlm.nih.gov/pubmed/36612262
http://dx.doi.org/10.3390/cancers15010262