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Targeting MYC Regulation with Polypurine Reverse Hoogsteen Oligonucleotides

The oncogene MYC has key roles in transcription, proliferation, deregulating cellular energetics, and more. Modulating the expression or function of the MYC protein is a viable therapeutic goal in an array of cancer types, and potential inhibitors of MYC with high specificity and selectivity are of...

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Detalles Bibliográficos
Autores principales: Valiuska, Simonas, Psaras, Alexandra Maria, Noé, Véronique, Brooks, Tracy A., Ciudad, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820101/
https://www.ncbi.nlm.nih.gov/pubmed/36613820
http://dx.doi.org/10.3390/ijms24010378