Type IV Collagen and SOX9 Are Molecular Targets of BET Inhibition in Experimental Glomerulosclerosis

Progressive glomerulonephritis (GN) is characterized by an excessive accumulation of extracellular (ECM) proteins, mainly type IV collagen (COLIV), in the glomerulus leading to glomerulosclerosis. The current therapeutic approach to GN is suboptimal. Epigenetic drugs could be novel therapeutic optio...

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Detalles Bibliográficos
Autores principales: Morgado-Pascual, José Luis, Suarez-Alvarez, Beatriz, Marchant, Vanessa, Basantes, Pamela, Tharaux, Pierre-Louis, Ortiz, Alberto, Lopez-Larrea, Carlos, Ruiz-Ortega, Marta, Rayego-Mateos, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820124/
https://www.ncbi.nlm.nih.gov/pubmed/36613933
http://dx.doi.org/10.3390/ijms24010486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820124/
https://www.ncbi.nlm.nih.gov/pubmed/36613933
http://dx.doi.org/10.3390/ijms24010486

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