Half-Life Extension and Biodistribution Modulation of Biotherapeutics via Red Blood Cell Hitch-Hiking with Novel Anti-Band 3 Single-Domain Antibodies

Small therapeutic proteins are receiving increased interest as therapeutic drugs; however, their clinical success has been limited due to their rapid elimination. Here, we report a half-life extension strategy via strategy via red blood cell red blood cell (RBC) hitch-hiking. This manuscript details...

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Detalles Bibliográficos
Autores principales: Nguyen, Toan D., Bordeau, Brandon M., Zhang, Yu, Mattle, Anna G., Balthasar, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820191/
https://www.ncbi.nlm.nih.gov/pubmed/36613917
http://dx.doi.org/10.3390/ijms24010475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820191/
https://www.ncbi.nlm.nih.gov/pubmed/36613917
http://dx.doi.org/10.3390/ijms24010475

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